Intelligent business processes composition based on mas, semantic and cloud integration (IPCASCI)

[EN]Component reuse is one of the techniques that most clearly contributes to the evolution of the software industry by providing efficient mechanisms to create quality software. Reuse increases both software reliability, due to the fact that it uses previously tested software components, and development productivity, and leads to a clear reduction in cost. Web services have become are an standard for application development on cloud computing environments and are essential in business process development. These services facilitate a software construction that is relatively fast and efficient, two aspects which can be improved by defining suitable models of reuse. This research work is intended to define a model which contains the construction requirements of new services from service composition. To this end, the composition is based on tested Web services and artificial intelligent tools at our disposal. It is believed that a multi-agent architecture based on virtual organizations is a suitable tool to facilitate the construction of cloud computing environments for business processes from other existing environments, and with help from ontological models as well as tools providing the standard BPEL (Business Process Execution Language). In the context of this proposal, we must generate a new business process from the available services in the platform, starting with the requirement specifications that the process should meet. These specifications will be composed of a semi-free description of requirements to describe the new service. The virtual organizations based on a multi-agent system will manage the tasks requiring intelligent behaviour. This system will analyse the input (textual description of the proposal) in order to deconstruct it into computable functionalities, which will be subsequently treated. Web services (or business processes) stored to be reused have been created from the perspective of SOA architectures and associated with an ontological component, which allows the multi-agent system (based on virtual organizations) to identify the services to complete the reuse process. The proposed model develops a service composition by applying a standard BPEL once the services that will compose the solution business process have been identified. This standard allows us to compose Web services in an easy way and provides the advantage of a direct mapping from Business Process Management Notation diagrams

Intelligent business processes composition based on multi-agent systems

This paper proposes a novel model for automatic construction of business processes called IPCASCI (Intelligent business Processes Composition based on multi-Agent systems, Semantics and Cloud Integration). The software development industry requires agile construction of new products able to adapt to the emerging needs of a changing market. In this context, we present a method of software component reuse as a model (or methodology), which facilitates the semi-automatic reuse of web services on a cloud computing environment, leading to business process composition. The proposal is based on web service technology, including: (i) Automatic discovery of web services; (ii) Semantics description of web services; (iii) Automatic composition of existing web services to generate new ones; (iv) Automatic invocation of web services. As a result of this proposal, we have presented its implementation (as a tool) on a real case study. The evaluation of the case study and its results are proof of the reliability of IPCASCI

An Enhanced Approach to Retrieve Learning Resources Over the Cloud

This study proposes AIREH (Architecture for Intelligent Retrieval of Educational content in Heterogeneous Environments) that is a model for the development of digital content retrieval based on the paradigm of virtual organizations of intelligent agents Learning objects have made it possible to create digital resources that can be reused in various didactic units. These resources are stored in repositories, and thus require a search process that allows them to be located and retrieved

Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor

Essential tremor (ET) is a common movement disorder with an estimated prevalence of 5% of the population aged over 65 years. In spite of intensive efforts, the genetic architecture of ET remains unknown. We used a combination of whole-exome sequencing and targeted resequencing in three ET families. In vitro and in vivo experiments in oligodendrocyte precursor cells and zebrafish were performed to test our findings. Whole-exome sequencing revealed a missense mutation in TENM4 segregating in an autosomal-dominant fashion in an ET family. Subsequent targeted resequencing of TENM4 led to the discovery of two novel missense mutations. Not only did these two mutations segregate with ET in two additional families, but we also observed significant over transmission of pathogenic TENM4 alleles across the three families. Consistent with a dominant mode of inheritance, in vitro analysis in oligodendrocyte precursor cells showed that mutant proteins mislocalize. Finally, expression of human mRNA harboring any of three patient mutations in zebrafish embryos induced defects in axon guidance, confirming a dominant-negative mode of action for these mutations. Our genetic and functional data, which is corroborated by the existence of a Tenm4 knockout mouse displaying an ET phenotype, implicates TENM4 in ET. Together with previous studies of TENM4 in model organisms, our studies intimate that processes regulating myelination in the central nervous system and axon guidance might be significant contributors to the genetic burden of this disorde

Metodologías activas flexibles para la enseñanza en los Estudios LGBTIQ+ de la UCM en modo sincrónico y asincrónico: Campus Virtual, Redes Sociales y entornos online como herramientas para la innovación docente y participación del alumnado

Memoria del Proyecto de Innovación Docente Curso 2022021, Ciencias Sociales nº 39

Territorio, Recursos Naturales y Ambiente: hacia una historia comparada : Estudio a través de Argentina, México, Costa Rica, Haití, Paraguay, Uruguay y Venezuela

Libro -- Universidad de Costa Rica. Centro de Investigaciones Geofísicas, 2014Nuestro objetivo principal ha sido establecer parámetros para una estudio comparativo de los recursos naturales y el ambiente, en función del territorio, en América Latina, a partir del estudio de casos particulares. Más concetamente, nos propusimos determinar: 1. las formas de conocimiento sobre el territorio, sus recursos naturales y su ambiente; y caracterizar los estilos científicos prevalecientes en cada etapa y región; 2. el papel de las instituciones y programas científicos en la formación de una tradición ambientalista local y las modalidades de desarrollo de estas temáticas a lo largo de la historia latinaomericana; 3. los parámetros de comprensión de las temáticas territoriales y ambientales desde las normativas y las políticas públicas de los estados; 4. los objetivos, áreas de investigación,campos de interés y resultados, según surgen de las publicaciones, productos y documentación científicos.Universidad de Costa Rica. Instituto Panamericano de Geografía e Historia (IPGH) Proyecto GEO 01.2013 – HIST. 02.2013.UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigaciones Geofísicas (CIGEFI